Papers

1. Chen GY, Gutman DA, Zerby SE, Ewing AG. Electrochemical monitoring of bursting exocytotic events from the giant dopamine neuron of Planorbis corneus. Brain Research. 1996 Sep;733(1):119-124.

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2. Hietpas PB, Bullard KM, Gutman DA, Ewing AG. Ultrathin slab gel separations of DNA using a single capillary sample introduction system. Analytical Chemistry. 1997 Jul;69(13):2292-2298.

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3. Anderson BB, Chen G, Gutman DA, Ewing AG. Dopamine levels of two classes of vesicles are differentially depleted by amphetamine. Brain Research. 1998 Mar;788(1-2):294-301.

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4. Kozminski KD, Gutman DA, Davila V, Sulzer D, Ewing AG. Voltammetric and pharmacological characterization of dopamine release from single exocytotic events at rat pheochromocytoma (PC12) cells. Analytical Chemistry. 1998 Aug;70(15):3123-3130.

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5. Anderson BB, Chen G, Gutman DA, Ewing AG. Demonstration of two distributions of vesicle radius in the dopamine neuron of Planorbis corneus from electrochemical data. Journal of Neuroscience Methods. 1999 May; 88(2):153-61.

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6. Rilling JK, Winslow JT, O’Brien DJ, Gutman DA, Hoffman JM, Kilts CD. Neural correlates of maternal separation in rhesus monkeys. Biological Psychiatry. 2001 Jan;49(2):146-157.

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7. Gutman DA, Owens MJ, Nemeroff CB. CRF Receptor Antagonists: A New Approach to the Treatment of Depression. Pharmaceutical News. 2001 Jan;8(3): 18-26.

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8. Gutman DA, Owens MJ, Nemeroff CB. Corticotropin-releasing factor antagonists as novel psychotherapeutics. Drugs of the Future. 2000 Jan;25(9): 923-931.

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9. Gutman DA, Nemeroff CB. Neurobiology of early life stress: rodent studies. Semin Clin Neuropsychiatry. 2002 Apr;7(2): 89-95.

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10. Rilling J, Gutman D, Zeh T, Pagnoni G, Berns G, Kilts C. A Neural Basis for Social Cooperation. Neuron. 2002 Jul;35(2): 395-405.

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11. Gutman DA, Nemeroff CB. Neurobiology of Early Life Stress: Rodent Studies. Seminars in Clinical Neuropsychiatry. 2002 Apr;7(2):89-95.

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12. Algararsamy S, Rouse ST, Junge C, Hubert GW, Gutman D, Smith Y, Conn PJ. NMDA-induced phosphorylation and regulation of mGluR5. Pharmacology Biochem Behav. 2002 Sep;73(2): 299-306.

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13. Mandell AJ, Selz KA, Owens MJ, Kinkead B, Shlesinger MF, Gutman DA, Arcuragi V. Cellular and behavioral effects of D2 dopamine receptor hydrophobic eigenmode-targeted peptide ligands. Neuropsychopharmacology. 2003 Jul;28(S):S98-107.

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14. Gutman DA, Owens MJ, Skelton KH, Thrivikraman KV, Nemeroff CB. The corticotropin-releasing factor 1 receptor antagonist R121919 attenuates the behavioral and endocrine responses to stress. J Pharmacol Exp Ther. 2003 Feb;304(2):874-880.

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15. Gutman DA, Nemeroff CB. Persistent central nervous system effects of an adverse early environment: clinical and preclinical studies. Physiology & Behavior. 2003 Aug;79(3): 471-478.

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16. Gutman DA, Owens MJ. Serotonin and norepinephrine transporter binding profile of SSRIs. Essential Psychopharmacology. 2006;7(1):35-41.

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17. Gutman DA, Gutman AR, Owens MJ, Nemeroff CB. Stress Neurobiology and Corticotropin-Releasing Factor. Psychiatryc Times. 2006 Sep 1 Vol 23:10.

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18. Skelton KH, Oren D, Gutman DA, Easterling K, Holtzman SG, Nemeroff CB, Owens MJ. The CRF1 receptor antagonist, R121919, attenuates the severity of precipitated morphine withdrawal. Eur J Pharmacol. 2007  Sep;571(1):17-24.

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19. Skelton KH, Gutman DA, Thrivikraman KV, Nemeroff CB, Owens MJ. The CRF1 receptor antagonist R121919 attenuates the neuroendocrine and behavioral effects of precipitated lorazepam withdrawal. Psychopharmacology. 2007 Jun;192(3):385-396.

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20. Johansen-Berg H, Gutman DA, Behrens TE, Matthews PM, Rushworth MF, Katz E, Lozano AM, Mayberg HS. Anatomical Connectivity of the Subgenual Cingulate Region Targeted with Deep Brain Stimulation for Treatment-Resistant Depression. Cereb Cortex. 2007 Oct;18(6):1374-1383.

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21. Gutman DA, Coyer JM, Boss-Williams KA, Owens MJ, Nemeroff CB, Weiss JM. Behavioral Effects of the CRF1 Receptor Antagonist R121919 in Rats Selectively Bred for High and Low Activity in the Swim Test. Psychoneuroendocrinology. 2008 Sep; 33(8):1093-101.

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22. Gutman DA, Holtzheimer PE, Behrens TE, Johansen-Berg H, Mayberg HS. A Tractography Analysis of Two Deep Brain Stimulation White Matter Targets for Depression. Biol Psychiatry. 2009 Feb 15;65(4): 276-282.

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23. Gutman DA, Owens MJ, Thrivikraman KV, Nemeroff CB. Persistent Anxiolytic Affects After Chronic Administration of the CRF(1) Receptor Antagonist R121919 in Rats. Neuropharmacology. 2011 Jun;60(7-8):1135-1141.

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24. Cooper LA, Kong J, Gutman DA, Wang F, Cholleti SR, Pan TC, et al. An integrative approach for in silico glioma research. IEEE transactions on bio-medical engineering. 2010 Oct;57(10):2617-2621.

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25. Kim M, Kurc T, Orso A, Cobb J, Gutman DA, Harrold MJ, Post A, Sharma A, Saltz J. An Informatics Framework for Testing Data Integrity and Correctness of Federated Biomedical Databases. AMIA Summits Transl Sci Proc. 2011;2011: 22-26.

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26. Kong J, Cooper LAD, Wang F, Gutman DA, Gao J, Chisolm C, et al. Integrative, Multi-modal Analysis of Glioblastoma Using TCGA Molecular Data, Pathology Images and Clinical Outcomes. IEEE Transactions on Information Technology in Biomedicine. 2011 Dec;58(12):3469-3474.

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27. Holtzheimer PE, Kelley ME, Gross RE, Filkowski MM, Garlow SJ, Barrocas A, Wint D, Craighead MC, Kozarsky J, Chismar R, Moreines JL, Mewes K, Posse PR,  Gutman DA, Mayberg HS. Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Unipolar and Bipolar Depression. Arch Gen Psychiatry. 2012 Feb;69(2):150-158.

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28. Cooper LA, Gutman DA, Chisolm C, Appin C, Kong J, Rong Y, Kurc T, Van Meir EG, Saltz JH, Moreno CS, Brat DJ. The Tumor Microenvironment Strongly Impacts Master Transcriptional Regulators and Gene Expression Class of Glioblastoma. Am J Pathol. 2012 May; 180(5):2108-19.

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29. Cooper LA, Kong J, Gutman DA, Wang F, Gao J, Appin C, Cholleti S, Pan T, Sharma A, Scarpace L, Mikkelsen T, Kurc T, Moreno CS, Brat DJ, Saltz JH. Integrated Morphologic Analysis for the Identification and Characterization of Disease Subtypes. J Am Med Inform Assoc. 2012 Mar-Apr; 19(2):317-23.

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30. Hecht EE, Gutman DA, Preuss TM, Sanchez MM, Parr LA, Rilling JK. Process Versus Product in Social Learning: Comparative Diffusion Tensor Imaging of Neural Systems for Action Execution-Observation Matching in Macaques, Chimpanzees, and Humans. Cereb Cortex. 2013 May;23(5):1014-1024.

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31. Fani N, Jovanovic T, Ely TD, Bradley B, Gutman DA, Tone EB, Ressler KJ. Neural Correlates of Attention Bias to Threat in Post-Traumatic Stress Disorder. Biol Psychol. 2012 May;90(2):134-142.

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32. Gutman DA, Keifer OP Jr, Magnuson ME, Choi DC, Majeed W, Keilholz S, Ressler KJ. A DTI Tractography Analysis of Infralimbic and Prelimbic Connectivity in the Mouse Using High-throughput MRI. Neuroimage. 2012 Nov;63(2):800-811.

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33. Fani N, King TZ, Jovanovic T, Glover EM, Bradley B, Choi K, Ely T, Gutman DA, Ressler KJ. White Matter Integrity in Highly Traumatized Adults with and without Post-Traumatic Stress Disorder. Neuropsychopharmacology. 2012 Nov; 37(12):2740-2746.

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34. Cooper L, Gutman DA, Long Q, Johnson BA, Cholleti SR, Kurc T, Saltz JH, Brat DJ, Moreno CS. The Proneural Molecular Signature is Enriched in Oligodendrogliomas and Predicts Improved Survival Among Diffuse Gliomas. PloS ONE. 2010 Sep;5(9): e12548.

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35. Wang F, Kurc T, Widener P, Pan T, Kong J, Cooper L, et al. High-Performance Systems for in Silico Microscopy Imaging Studies. In: Lambrix P, Kemp G, editors. Data Integration in the Life Sciences. Lecture Notes in Computer Science. 6254: Springer Berlin Heidelberg; 2010. p. 3-18.

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36. Gutman DA, Magnuson M, Majeed W, Keifer OP Jr, Davis M, Ressler KJ, Keilholz S. Mapping of the Mouse Olfactory System with Manganese-Enhanced Magnetic Resonance Imaging and Diffusion Tensor Imaging. Brain Struct Funct. 2013 Mar;218(2):527-537.

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37. Gutman DA, Cooper LAD, Hwang S, Flanders A, Brat D.  MR Imaging Predictors of Molecular Profile and Survival: A Multi-Institutional Study of the TCGA Glioblastoma Data Set.  Radiology. 2013 May; 267(2):560-569.

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38. Rutledge WC, Kong J, Gao J, Gutman DA, Cooper LA, Appin C, et al. Tumor-infiltrating lymphocytes in glioblastoma are associated with specific genomic alterations and related to transcriptional class. Clinical Cancer Research. 2013 Sep;19(18):4951-4960.

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39. Fani N, Gutman D, Tone EB, Almli L, Mercer KB, Davis J, et al. FKBP5 and attention bias for threat: associations with hippocampal function and shape. JAMA psychiatry. 2013 Apr;70(4):392-400.

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40. Gutman DA, Cobb J, Somanna D, Park Y, Wang F, Kurc T, et al. Cancer Digital Slide Archive: an informatics resource to support integrated in silico analysis of TCGA pathology data. Journal of the American Medical Informatics Association. 2013 Nov;20(1):1091-1098.

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41. Hecht EE, Murphy LE, Gutman DA, Votaw JR, Schuster DM, Preuss TM, et al. Differences in neural activation for object-directed grasping in chimpanzees and humans. The Journal of neuroscience. 2013 Aug;33(35):14117-1434.

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42. Jain R, Poisson L, Narang J, Gutman D, Scarpace L, Hwang SN, et al. Genomic mapping and survival prediction in glioblastoma: molecular subclassification strengthened by hemodynamic imaging biomarkers. Radiology. 2013 Apr;267(1):212-20.

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43. Howell BR, Godfrey J, Gutman DA, Michopoulos V, Zhang X, Nair G, et al. Social Subordination Stress and Serotonin Transporter Polymorphisms: Associations With Brain White Matter Tract Integrity and Behavior in Juvenile Female Macaques. Cerebral cortex. 2013 (in print)

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44. Colen, R. R., M. Vangel, J. Wang, D. A. Gutman, S. N. Hwang, M. Wintermark, R. Jain, M. Jilwan-Nicolas, J. Y. Chen, P. Raghavan, C. A. Holder, D. Rubin, E. Huang, J. Kirby, J. Freymann, C. C. Jaffe, A. Flanders, T. G. P. R. Group and P. O. Zinn (2014). “Imaging genomic mapping of an invasive MRI phenotype predicts patient outcome and metabolic dysfunction: a TCGA glioma phenotype research group project.” BMC Med Genomics 7: 30.

(Link to Pubmed)

45. Gutman, D. A., W. D. Dunn, Jr., J. Cobb, R. M. Stoner, J. Kalpathy-Cramer and B. Erickson (2014). “Web based tools for visualizing imaging data and development of XNATView, a zero footprint image viewer.” Front Neuroinform 8: 53.

(Link to Pubmed)

46. Hecht, E. E., D. A. Gutman, N. Khreisheh, S. V. Taylor, J. Kilner, A. A. Faisal, B. A. Bradley, T. Chaminade and D. Stout (2014). “Acquisition of Paleolithic toolmaking abilities involves structural remodeling to inferior frontoparietal regions.” Brain Struct Funct.

(Link to Pubmed)

47. Jain, R., L. M. Poisson, D. Gutman, L. Scarpace, S. N. Hwang, C. A. Holder, M. Wintermark, A. Rao, R. R. Colen, J. Kirby, J. Freymann, C. C. Jaffe, T. Mikkelsen and A. Flanders (2014). “Outcome prediction in patients with glioblastoma by using imaging, clinical, and genomic biomarkers: focus on the nonenhancing component of the tumor.” Radiology 272(2): 484-493.

(Link to Pubmed)

48. Nicolasjilwan, M., Y. Hu, C. Yan, D. Meerzaman, C. A. Holder, D. Gutman, R. Jain, R. Colen, D. L. Rubin, P. O. Zinn, S. N. Hwang, P. Raghavan, D. A. Hammoud, L. M. Scarpace, T. Mikkelsen, J. Chen, O. Gevaert, K. Buetow, J. Freymann, J. Kirby, A. E. Flanders, M. Wintermark and T. G. P. R. Group (2014). “Addition of MR imaging features and genetic biomarkers strengthens glioblastoma survival prediction in TCGA patients.” J Neuroradiol.

(Link to Pubmed)

49. Stevens, J. S., L. M. Almli, N. Fani, D. A. Gutman, B. Bradley, S. D. Norrholm, E. Reiser, T. D. Ely, R. Dhanani, E. M. Glover, T. Jovanovic and K. J. Ressler (2014). “PACAP receptor gene polymorphism impacts fear responses in the amygdala and hippocampus.” Proc Natl Acad Sci U S A 111(8): 3158-3163.

(Link to Pubmed)